Written by: Tennant Products Editorial Team
Reviewed by: Patsy Scott, CHN (Certified Holistic Nutritionist)
Last Updated: February 2026
TL;DR
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Dr. Tennant’s® GI 60 Probiotic Formula is a synbiotic supplement designed for gut, immune, and gut–brain support.
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It delivers 60 billion CFUs from four clinically studied probiotic strains
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The formula includes targeted prebiotics to nourish beneficial bacteria where they colonize.
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MAKTREK® Bi-Pass Technology is used to help probiotics survive stomach acid and reach the gut.
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Dr. Tennant’s® GI 60 Probiotic Formula supports digestive comfort, gut barrier health, immune resilience, and stress and mood balance.
What Is Dr. Tennant’s® GI 60 Probiotic Formula?
Dr. Tennant’s® GI 60 Probiotic Formula is a next-generation synbiotic probiotic formula formulated to support digestive comfort, gut lining integrity, immune health, and the gut–brain connection.
The GI 60 represents an evolution in probiotic formulation, bringing together clinically studied strains, targeted prebiotics, and advanced delivery technology to support everyday gut health.
Why Dr. Tennant’s® GI 60 Probiotic Formula Uses a Targeted Synbiotic Approach
What Does Synbiotic Mean?
A synbiotic formula combines:
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Probiotics, which are beneficial bacteria
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Prebiotics, which are specialized fibers that nourish those bacteria
This pairing is designed to support probiotic survival, colonization, and activity in the gut. The goal is not just to add bacteria, but to help them thrive once they arrive.
Why Probiotics Matter for Whole-Body Health
The gut microbiome influences far more than digestion. A balanced gut environment supports:
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Digestive comfort and regularity
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Nutrient absorption
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Gut barrier integrity
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Immune signaling
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Gut–brain communication related to stress and mood
Modern factors such as stress, antibiotics, highly processed foods, and environmental toxins may disrupt this balance. When that happens, people may experience bloating, irregularity, discomfort, or a general feeling that the body is out of sync.
Probiotics may help restore balance by replenishing beneficial bacteria and supporting a healthier gut environment.
Why We Focused on Four Clinically Studied Probiotic Strains
Advances in probiotic research have helped guide more intentional strain selection for daily gut health support.
When developing Dr. Tennant’s® GI 60 Probiotic Formula, each strain was evaluated for:
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Survivability through digestion
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Clinical research support
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Meaningful daily benefits
Rather than using many overlapping strains, the formula was refined to include four well-studied, high-performing strains that work together to support the core functions most people want from a daily probiotic.
The Four Clinically Studied Probiotic Strains in Dr. Tennant’s® GI 60 Probiotic Formula
Lactobacillus acidophilus La-14
Digestive Balance and Immune Support
La-14 is a clinically studied probiotic strain shown to support digestive balance and overall gut microbiome health. It is suitable for daily use and helps maintain a balanced gut environment that supports immune function.
Bifidobacterium lactis Bl-04
Immune and Respiratory Health Support
Bl-04 is one of the most researched probiotic strains for immune support. It is associated with healthy immune response and immune resilience, including upper respiratory wellness.
Lactobacillus plantarum Lp-115
Digestive Comfort and Gut Barrier Support
Lp-115 is a resilient strain known for its ability to survive digestion and support gut lining integrity. It helps support digestive comfort and balanced immune signaling through the gut.
Lactobacillus paracasei Lpc-37®
Stress, Mood, and Gut–Brain Support
Lpc-37® is a clinically studied psychobiotic strain that supports the gut–brain connection. Research suggests it may help support stress resilience, mood balance, and overall well-being through immune and nervous system signaling in the gut.
MAKTREK® Bi-Pass Technology for Probiotic Survival
Many probiotics do not survive stomach acid long enough to reach the intestines.
Dr. Tennant’s® GI 60 Probiotic Formula includes MAKTREK® Bi-Pass Technology, which is designed to protect probiotics as they move through digestion. This helps ensure more beneficial bacteria arrive in the gut alive, where they can provide support.
This technology is designed for real-world performance, not just label claims.
The Role of Prebiotics in Dr. Tennant’s® GI 60 Probiotic Formula
Prebiotics act as the fuel that helps beneficial bacteria survive and thrive.
Dr. Tennant’s® GI 60 Probiotic Formula includes two targeted prebiotics selected to support the strains in this formula.
Fructooligosaccharides (FOS) from Chicory Root
FOS is a clinically supported short-chain prebiotic that helps nourish lactobacilli and bifidobacteria. It supports a healthy gut environment and bacterial balance.
Marine Polysaccharides from Marine Algae
Marine polysaccharides are an innovative fiber source that supports gut environment health and may assist probiotic survival during digestion.
Together, these prebiotics support synbiotic synergy and help beneficial bacteria colonize effectively.
How Gut Health Supports Immune Function
A large portion of immune activity is associated with the gastrointestinal tract.
Beneficial bacteria may support immune health by:
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Helping inhibit the growth of unwanted microbes
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Supporting balanced immune signaling
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Supporting IgA activity, an important immune defense antibody
Supporting a balanced microbiome is one way to support everyday immune resilience.
How to Take Dr. Tennant’s® GI 60 Probiotic Formula
Take Dr. Tennant’s® GI 60 Probiotic Formula as directed on the label.
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Take 2 capsules daily
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Take with 4 to 8 oz of filtered water
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Can be taken with food or without food
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Designed for daily use
For best results, take consistently each day.
Important Use Notes
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Do not take GI 60 at the same time as iodine, as this may reduce effectiveness
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If you are new to probiotics, consider starting slowly and increasing as your body adjusts
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Always consult your healthcare provider if you have questions or are taking medications, as supplements may affect certain medications
FAQs
What makes Dr. Tennant’s® GI 60 Probiotic Formula different from other probiotics?
Dr. Tennant’s® GI 60 Probiotic Formula combines clinically studied probiotic strains, targeted prebiotics, and advanced delivery technology to support digestive and immune health.
Is Dr. Tennant’s® GI 60 Probiotic Formula probiotic or a synbiotic formula?
Dr. Tennant’s® GI 60 Probiotic Formula is synbiotic. It contains both probiotics and prebiotics designed to work together for better effectiveness.
Who is Dr. Tennant’s® GI 60 Probiotic Formula designed for?
GI 60 is designed for adults seeking daily support for digestion, gut barrier health, immune resilience, and gut–brain wellness.
How long does it take to notice benefits?
Some people notice digestive comfort within days, while others may need several weeks of consistent use for full benefits.
Can Dr. Tennant’s® GI 60 Probiotic Formula be taken daily?
Yes. GI 60 is formulated for daily use as part of a long-term gut health routine.
It’s your body. It’s your life. Ingredients matter.
Featured Products in This Article:
Dr. Tennant’s® GI 60 Probiotic Formula provides a biological synergy with “good bacteria” (probiotics), “food for the probiotics” (prebiotics), and a protective delivery technology to maximize probiotic effectiveness and support a healthier GI system.
DISCLAIMER: This content is intended for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or qualified healthcare provider before starting any new supplement, especially if you are pregnant, nursing, taking medications, immunocompromised, or have an existing health condition. Individual needs and responses may vary. Use this information as a guide and modify based on your healthcare provider’s recommendations.
