From Growing Hearts in the Lab<br>To Personalized Supplementation:<br>Key Learnings From Abundance 360

From Growing Hearts in the Lab
To Personalized Supplementation:
Key Learnings From Abundance 360

Discovering the Future of Health and Longevity: Insights from Abundance 360 Conference

We’ve occasionally written about events of possible interest to you, where one of our staff members have attended an event or conference. Today, Dr. Tennant’s son John writes about his experience at the Abundance 360 Conference, where health longevity was a main theme and speakers like Dr. David Sinclair, Dr. Mark Hyman and Dr. Doris Taylor provided amazing insights.

 

Hello, I’m John Tennant, a co-owner of Tennant Products. I went to an amazing conference in March 2022 called “Abundance 360,” and I wanted to share with you some of the insights gleaned.

Abundance 360 attending John Tennant
Here I am at the conference with one of our customers, Dr. Selene Castrejon-Dunham, and Dave Asprey, the father of biohacking.

 

Abundance 360 is an annual technology conference organized by Peter Diamandis, where he discusses the latest trends and predictions in exponential technologies like AI and longevity, and how they can be leveraged to solve humanity's grand challenges and create a better future for all. This year, the longevity-focused themes included:

Dr. David Sinclair: Remaining Young + Age Reversal & Epigenetics

David Sinclair Abundance 360

Let’s start with David Sinclair, PhD. Dr Sinclair is a renowned biologist and geneticist who is considered a leading expert on aging research. His work focuses on studying the genetic and environmental factors that contribute to aging and age-related diseases and developing interventions that can slow down or even reverse the aging process. He has made groundbreaking discoveries in the field of epigenetics, which is the study of how changes in gene expression can affect health and aging. 

Dr. Sinclair's work focuses on extending the human lifespan. One of the most interesting parts of his conversation was when he said this: 

“There is no law that says we must age.” 

What he meant is that there is no inherent biological law that says we must age. According to Dr. Sinclair, aging is not an inevitable result of the passage of time, but rather a result of accumulated damage at the cellular and molecular levels. By repairing this damage and resetting the body's biological processes, it may be possible to reverse the aging process and restore youthful vitality.

Dr. Sinclair's research has identified several promising interventions that can slow down or even reverse aging, including caloric restriction, exercise, and the use of certain supplements and drugs. His work has the potential to transform our understanding of aging and change the way we approach healthcare and wellness.

Here was his summary:

  • Exercise! Regular exercise is one of the most effective ways to slow down the aging process and promote longevity. Exercise has been shown to enhance mitochondrial function, reduce oxidative stress, and increase the body's production of antioxidants, all of which can help to protect against cellular damage and promote healthy aging.

  • Restrict your calories. We don’t need to eat as much as we do.

  • Supplement your diet with the following:

    • NMN: This helps increase strength. (Tennant Products does not sell NMN at this time).

    • Rapamycin: Dr. Sinclair likes this for longevity, but it requires a doctor’s prescription.

    • CoQ10: Dr. Sinclair sees a relationship between this antioxidant and longevity by improving mitochondrial functioning. (Tennant Products Restore contains Ubiquinol CoQ10.)

    • NAD: This is required for life, i.e. the chemical processes in the body. NAD boosts the mitochondrial processes.

      NAD/NADH is one of our favorite ingredients. It functions as a biological spark plug in the human body and ensures activity and vitality. Of course, we use the best available version: PANMOL®, the biologically active form of vitamin B3. NADH is easier for your body to absorb and use relative to the NAD-related versions of Niacin that you might find on Amazon. NADH is the strongest energy donor and the strongest electron donor (antioxidant) for the human organism.

      Due to these properties however, NADH is also very unstable when exposed to light and oxygen. Therefore, most versions of NAD/NADH lose their effectiveness very quickly. PANMOL, which we have in all versions of our Restore product line, uses a patented method to make NADH non-perishable for years without the use of chemical substances and thus preserve its effectiveness. This special micro-encapsulation also allows NADH to be combined with other active ingredients.

       

      Dr. Mark Hyman: Functional Medicine and Gene Expression

      Abundance 360 Dr. Mark Hyman

      Next up was Dr. Mark Hyman. Mark Hyman is a medical doctor, best-selling author, and advocate of functional medicine. He is the director of the Cleveland Clinic Center for Functional Medicine and the chairman of the Institute for Functional Medicine. Functional medicine seeks to treat the underlying causes of disease by addressing the individual's unique biochemistry, genetics, and environment. Dr. Hyman is well known in our community for his nutritional and lifestyle interventions. One of the most interesting parts of his discussion was this:

      “Your genes do not define you; it’s not your genes, it’s your gene expressions.”

      Dr. Mark Hyman believes that gene expression is not fully predetermined by genetics, but can be influenced by lifestyle factors such as diet, stress, and environmental toxins. He advocates for the use of functional medicine approaches to optimize gene expression, which can help to prevent and treat chronic diseases. By understanding the epigenetic factors that impact gene expressions, such as diet, stress management, and detoxification, individuals can take control of their health and well-being.

      Dr. Hyman emphasizes the importance of personalized medicine that takes into account each individual's unique genetics, environment, and lifestyle factors, to optimize gene expression and promote longevity and wellness.

      Navin Jain: Hyper-personalized Supplementation

      Abundance 360 CEO of Viome Naveen Jain

      In this vein, the CEO of Viome, Naveen Jain, also spoke about hyper-personalization. Viome is known for taking your blood, saliva, and stool samples and then "customizing" supplements for you based on this data. We occasionally get asked about whether Tennant Products will move into this business model. As of right now, here is our take on this approach:

        Number one, we love the idea. That said, a test is a sample of a single moment in time. Let’s say that you took a blood test on Monday, and then lived your life for seven days which included: eating, exercising, flying on an airplane, getting woken up in the middle of the night, feeling stressed at work and at home, and so on. Your next week’s test would likely be slightly different, and therefore the "recommended" doses and possibly supplement recommendations would be different.

        Also, the time between your test and when you receive and start taking the supplements means that your supplementation is “behind the hockey puck.” 

          We take an alternative approach. Dr. Tennant has designed a single product – Restore – to give you everything your body needs to create new, healthy cells. Restore will go a long way to set your baseline health. Your specific needs can then be supplemented on top of this healthy baseline. We might also note that, despite the appearance of the highest quality, we assure you that many of these hyper-personalization products use low or mid-grade ingredients that we would never sell...in any business model!

          A final comment on this:

          Viome’s (and others’) stool sample test gives good visibility into your Microbiome health. The microbiome, which consists of trillions of microorganisms that live in and on our bodies, plays a crucial role in our overall health and well-being. These microbes, which include bacteria, viruses, and fungi, have a significant influence on our immune system, metabolism, and brain function.

          The microbiome helps to break down food, produce essential vitamins and nutrients, and keep harmful pathogens in check. Imbalances or disruptions in the microbiome have been linked to a host of health problems, including autoimmune diseases, allergies, mood disorders, and obesity. Maintaining a healthy and diverse microbiome through diet, lifestyle factors, and the judicious use of antibiotics, probiotics, and prebiotics is essential for optimal health and well-being.

          Finally, the microbiome also plays a critical role in maintaining the integrity of the gut lining. Thus, it is becoming increasingly evident that a healthy and diverse microbiome is essential for optimal health and that imbalances in the microbiome can contribute to a wide range of health problems.

          We have a great baseline product called Microbiome Support. With more than ten trademarked, supercharged versions of key ingredients such as Setria® Glutathione, Dr. Tennant’s® Microbiome Support can help reset the microbiota; improve your intestinal wall integrity by helping to restore tight junctions; and can support the cleaning, healing, and restoration of your gut. 

          Dr. Doris A. Taylor: Organ & Limb Regeneration (hearts)

          Abundance 360 Dr. Doris A. Taylor

          Dr. Doris A. Taylor is a biomedical scientist and a pioneer in the field of regenerative medicine. Her research focuses on developing new treatments for heart disease, one of the leading causes of death worldwide. My brother Tom passed away last year from a heart attack, so to see what’s on the scientific roadmap for heart disease was, for me, hopeful. When giving the audience an overview of current heart transplants, she quoted this line:

          “In our line of work, someone has to die for someone else to live.” 

          Dr. Taylor has made groundbreaking discoveries in the use of stem cells and tissue engineering to repair and regenerate damaged heart tissue. Her work has demonstrated the potential for these technologies to improve heart function and reduce the need for heart transplants. Dr. Taylor's innovative approaches to cardiac repair have the potential to revolutionize the treatment of heart disease and transform the lives of millions of people around the world. Dr. Taylor has developed innovative methods for growing new heart tissue in the lab. (See image below.)

          Aundance 360 tissue regenerative treatments heart

           

          Her goal is crazy: Make bioengineered personalized human hearts available within five years! 

          Dr. Taylor’s work has opened up new avenues for the development of regenerative treatments for heart disease. Her tone of scientific hope was contagious!

          In conclusion, my biggest takeaway from the Abundance 360 conference is the concept of “bridge-to-bridge-to-bridge.” The pace of technological change, and our understanding of the underpinnings of chronic disease, get better every day. Our task is clear: get yourself healthy and stay healthy! By doing so, you keep yourself in the game so that you just might intercept the process or technology that helps cure you when you most need it. From a mathematical perspective, although it’s not linear, “bridge-to-bridge-to-bridge” says that you get an extra three months of life for every year you stay alive. 

          John Tennant

          It’s your body. It’s your life. Ingredients matter.

           


          Featured Products in This Article:

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          Dr. Tennant’s® Gut Bootcamp:

          Helps reset the balance of the microbiome and mycobiome within the gut, in addition to helping the body cleanse and detox while improving intestinal wall integrity, reducing inflammation and supporting immune system modulation and regularity. 

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