The Essential Role of Nitric Oxide<p> in Human Health

The Essential Role of Nitric Oxide

in Human Health

Nitric Oxide (NO), a critical molecule in the human body, has been gaining increasing attention for its vital role in maintaining health and preventing disease. This is especially important for individuals over forty as out bodies ability to make nitric oxide decreases.

Did You Know?
As we age, we lose 85% of our ability to make nitric oxide.

Understanding Nitric Oxide

Nitric Oxide is a gas comprised of one nitrogen (N) and one oxygen (O) atom, playing a crucial role as a signaling molecule in various body systems. Its importance was highlighted when the 1998 Nobel Prize in Physiology or Medicine was awarded for discoveries regarding its function in the cardiovascular system.

nitric oxide production as we age

Try Nitric Oxide Now

Key Functions of Nitric Oxide

  1. Cardiovascular Health: Nitric Oxide is instrumental in regulating blood flow and blood pressure. It causes vasodilation, which increases blood flow and reduces hypertension, which is a major risk factor for cardiovascular disease.

  2. Topical Applications: In skin care, Nitric Oxide helps in rejuvenating skin, reducing acne, and aiding in wound healing.

  3. Immune System Support: It plays a role in activating immune cells and combating pathogens.

  4. Aiding Stem Cells: It contributes to the environment conducive for stem cell repair and differentiation.

  5. Inflammation Response: It acts as an anti-inflammatory agent while also mediating pro-inflammatory cells based on the body's needs.

  6. Additional Roles: Its functions extend to the respiratory system, nervous system, and gastrointestinal-urogenital tract.

The Challenge of Maintaining Nitric Oxide Levels

Producing sufficient Nitric Oxide is effortless for younger individuals, but the capability diminishes with age. Most people over forty are found to be Nitric Oxide deficient. This deficiency can lead to various health issues, including hypertension, atherosclerosis, and coronary heart disease.

Natural Production of Nitric Oxide

  1. Endothelial Production: Through the endothelial cells in blood vessels using the eNOS system.

  2. Saliva-based Production: Involves the breakdown of nitrates from foods like leafy green vegetables, interacting with bacteria at the back of the tongue.

Try Nitric Oxide Now

Addressing Nitric Oxide Deficiencies

To counteract deficiencies, one should:

  • Include nitrate-rich foods such as leafy greens in their diet.
  • Avoid practices that kill beneficial bacteria in the mouth, like excessive use of antiseptic mouthwash.
  • Maintain a healthy stomach pH level.
  • Don't use mouthwash.
  • Consume a high-quality Nitric Oxide supplement like N1O1 Lozenges.

The Potential of Nitric Oxide Supplements

For those over forty, or anyone struggling to maintain optimum Nitric Oxide levels, supplements can be beneficial. Products like N1O1 Lozenges offer a convenient way to enhance Nitric Oxide levels, supporting cardiovascular health, healthy arterial function, and maintaining healthy blood pressure levels.

Dietary Sources of Nitric Oxide

While supplements are helpful, a diet rich in nitric oxide can significantly boost levels. Foods high in nitrates, such as beetroot juice, leafy greens, garlic, and pomegranates, are excellent sources.

Risk of Excess Nitric Oxide

While deficiency is a concern, excessive Nitric Oxide can lead to low blood pressure, nausea, and other symptoms like dizziness and shortness of breath. However, fears of extreme conditions like methemoglobinemia are unfounded for average dietary consumption.(1)

Nitric Oxide's role in human health is undeniable, especially as one ages. Understanding its importance and maintaining its levels through diet or supplements can lead to significant health benefits. As research continues, the potential of Nitric Oxide in various therapeutic areas remains a promising field.


(1) Bryan, Nathan S. “But I Thought Nitrite and Nitrate Were Toxic.” Functional Nitric Oxide Nutrition, Crescendo Publishing, 2018.

Read More About About Nitric Oxide

It’s your body. It’s your life. Ingredients matter.


Featured Products in This Article:

Nitric oxide lozenges product image

N1O1 Nitric Oxide Lozenges: Unlock superior cellular vitality with N1O1, meticulously developed by world-renowned expert Dr. Nathan S. Bryan. Designed to seamlessly enhance your body's Nitric Oxide production. N1O1 not only supports robust cardiovascular health and optimized nutrient delivery to cells, but also champions your overall well-being by supporting cognitive function, memory, and offering potent antioxidant support.

shop now

N1O1 Nitric OxideTM Activating Serum with Antioxidants: A patent-pending, innovative dual chamber technology that produces nitric oxide gas when the contents of both chambers are mixed together. N1O1 Nitric Oxide™ Activating Serum contains Vitamin C that works synergistically with nitric oxide to improve the appearance of skin.

shop now

Functional Nitric Oxide Nutrition: The latest book from Dr. Nathan Bryan educates readers on the importance of nitric oxide. It clearly illustrates that diet and lifestyle modifications can significantly improve nitric oxide production and arm the reader with information so they can begin to implement what they have learned into their daily life.

shop now


The information provided on this page is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice. Always work with your healthcare provider before starting any supplement program.