N1O1 Nitric Oxide Serum
N1O1 Nitric Oxide Serum
N1O1 Nitric Oxide Serum

N1O1 Nitric Oxide Serum

Regular price $180.00
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New Name and New Look: Pneuma is now N1O1 Nitric Oxide TM Activating Serum with antioxidants and now offers 30% more applications in each bottle! 

N1O1 Nitric OxideTM Activating Serum with antioxidants (formerly called Pneuma) for the skin helps with:

  • Improving the appearance of fine lines and wrinkles
  • Overall tone, texture and clarity of the skin
  • Softening the signs of aging

Loss of Nitric Oxide with aging leads to increased signs of aging including poor complexion, loss of barrier function and increased appearance of fine lines and wrinkles. Therefore, in people that have lost the ability to produce Nitric Oxide by the cells in the skin, Nitric Oxide has to be produced for them. 

N1O1 Nitric Oxide™ Activating Serum is a patent pending, innovative dual chamber technology that produces Nitric Oxide gas when the contents of both chambers are mixed together. That is the beauty of the N1O1 Nitric Oxide™ Activating Serum. If your body cannot produce Nitric Oxide, N1O1 does it for you.  

1-Month supply in each bottle

Learn More About Nitric Oxide

Disclaimer: The information provided on these product pages is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice. Always work with your healthcare provider before starting any supplement program.


N1O1 Nitric Oxide™ Activating Serum with antioxidants is a patent pending serum that contains Vitamin C and works synergistically with Nitric Oxide to improve the appearance of skin.

N1O1’s synergistic Nitric Oxide dual chamber delivery system contains a high-concentration of powerful antioxidants proven in peer-review studies to help prevent the free radical damage that can lead to the appearance of premature aging.

Because there are no chemical preservatives that can permeate into your skin, the all-natural antioxidants may develop a slight amber hue. This is perfectly normal, does not affect N1O1’s effectiveness and lets you know N1O1 Activating Serum contains only the healthiest ingredients.

Specific Ingredients include: Water, Ascorbic acid, Polysorbate 20, hydroxyethylcellulose, sodium nitrite, d-Tocopheryl Acetate, dehydroacetic acid, benzyl alcohol, sodium sulfite, sodium metabisulfite, tetrasodium EDTA.

  • Fragrance Free
  • Phthalate & Paraben Free
  • No Animal Testing
  • Patent Pending Technology

Suggested Use 

Use in the morning and evening on clean skin. 

  • Dispense a single pump from each chamber. Mix together and apply to the face and neck. 
  • Allow serum to fully absorb 1-2 minutes before applying or continuing with your normal daily skin care regime. 

N1O1 Nitric Oxide™ Activating Serum can be used as a stand-alone skin treatment or as a primer for your existing skin care regime. N1O1 prepares your skin to make any skin care treatment work better.

When serums from the dual chambers are mixed together, the Nitric Oxide is activated. As a result of the Nitric Oxide activation certain skin types could show a pink tone for a few minutes. 

It is common for Vitamin C to turn an amber color over time. This does not affect the activity or benefits of this product.

Customer Reviews
4.7 Based on 6 Reviews
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  • face
  • Miraculous
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  • Tennant
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Dr. Recommended

Dr. Recommended

United States United States
I recommend this product

Used during a facial

Used during a facial

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Love this product

Love this product, thank you Tennant team!

Abby T.
United States United States
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Where has this been all my life?

Miraculous really. My skin LOVES this product! My face looks smooth, healthy and I’m getting unexpected comments like, “…your skin looks amazing!” At 77 this is a wonderful thing to hear:)

Mary R.
United States United States
I recommend this product


fair. it is somewhat showing improvement if my skin but not very noticeable.